流式抗体/ AF/LE Purified Anti-Mous

CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Programmed Death-1;PD-1

Q02242

18566

29F.1A12

Rat

Mouse

FCM;Block;Neut

Rat IgG2a, κ

AF/LE Purified Rat IgG2a, κ Isotype Control[2A3]

None (AF/LE)

0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

This product can be stored at 2-8°C for 12 months. Do not freeze.

12个月

冰袋