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文献和实验Pathways Implicated in Stem Cell Migration: The SDF-1/CXCR4 Axis
The hallmark of hematopoietic stem and progenitor cells (HSPCs) is their motility, which is essential for their function, such as recruitment upon demand. Stromal Derived Factor-1 (SDF-1, CXCL12) and its major receptor CXCR4 play major roles
Primary Isolation and Culture of Chicken Osteoclasts
Bone is a dynamic tissue that is continually remodeled throughout life. Such remodeling is carried out by the coordinated actions of two bone cell types: bone-resorbing osteoclasts (OCs) which are uniquely capable of dissolving and removing
ABSTRACT Fibroblast growth factor (FGF) signaling plays a signifigant role in embryonic development. Particularyl, FGFs are implicated in mediating epithelial-mesenchymal interactions by means of regulating cell proliferation
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