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文献和实验Chemical Mutational Analysis of Glucocorticoid Receptor
This chapter describes a chemical method for mutational analysis of the human glucocorticoid receptor (hGR) cDNA. Corticosteroid-resistant (CR) asthma is associated with in vitro and in vivo defects in mononuclear cell function
High-Yield Purification of Functionally Active Glucocorticoid Receptor
The glucocorticoid receptor (GR) resides in the cytoplasm as a complex with chaperones. Upon ligand association, GR shuttles into the nucleus, and binds to its hormone response elements to control expression of particular genes
乙 -受体(β -受体) β -receptor 儿茶酚胺的受体之一。一般呈抑制反应,即一旦接受儿茶酚胺的作用,便产生血管、子宫、支气管等器管的舒张和心肌兴奋。由异丙基肾上腺素( isopr-oterenol)的作用也可产生这种反应。而 3, 4-二氯异丙基肾上腺素( DCI)、心得安等β -受体阻断剂可阻断其作用。
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