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文献和实验Quantifying Aβ1–40 and Aβ1–42 Using Sandwich-ELISA
The role of Aβ accumulation in the pathogenesis of Alzheimer’s disease (AD) is supported by genetic studies showing that mutations in the amyloid-β precursor protein (APP) that alter Aβ production are linked to a subset of familial AD (FAD) cases
Evaluating B-Cells: From Bone Marrow Precursors to Antibody-Producing Cells
, but can also be used to evaluate cell function, activation, and division. Here, we will combine the use of FACS analysis and ELISA techniques to identify murine bone marrow and peripheral B-cell subsets. The main function of B cells, derived through a multistage
Functional Cloning of Genes Regulating Apoptosis in Neuronal Cells
by doxorubicin and is detected with a fluorometric caspase 3 assay. Moreover, we describe also the screen of the library to identify genes regulating the processing of the β-amyloid (Aβ) precursor protein (APP), the protein associated
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