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文献和实验transcription activator?like effector nucleases (TALENs) are broadly useful tools for performing targeted genome editing in a wide variety of organisms and cell types including plants, zebrafish, C. elegans , rat, human somatic cells, and human pluripotent stem
Detection of Intact Transcription Factors in Human Neutrophils
cytokines produced by neutrophils are generally encoded by immediate-early response genes, which in turn depend on the activation of transcription factors such as those belonging to the nuclear factor (NF)-κB and signal transducers and activators
Activator-Dependent Acetylation of Chromatin Model Systems
1 promoter. Using this system as an example, here we describe the use of a combination of biochemical and biophysical methods to investigate the effect of activator-dependent acetylation on higher order chromatin structure and transcription by RNA polymerase
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