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- 详细信息
- 文献和实验
- 技术资料
- 保质期:
12个月
- 供应商:
广州华韵生物科技有限公司
- 应用范围:
FCM
- 规格:
25μg
请联系华韵客服获取说明书。
产品简介:
| Background |
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.
|
| Alternate Names |
2'-phospho-ADP-ribosyl cyclase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;ADPRC 1;CD38;Cyclic ADP-ribose hydrolase 1;T10;cADPr hydrolase 1
|
| Swissprot |
P28907
|
| Gene ID |
952
|
| Clone No |
HIT2
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Application |
FCM
|
| Isotype |
Mouse IgG1, κ
|
| Isotype Control |
Purified Mouse IgG1, κ Isotype Control[MOPC-21]
|
| Conjugation |
Unconjugated
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验Method for Purification of Human Hematopoietic Stem Cells by Flow Cytometry
HSCs and progenitors. In order to subfractionate CD34+ cells by these markers, the cells can be further purified by flow cytometry. HSCs can be further enriched into a Thy-1+ (3 –7 ), CD38-lo (8 –10 ), Thy-1+ CD38-lo (11 ), or AC133
. We describe a method for the isolation from human fetal liver of highly purified candidate HSCs and progenitors based on the phenotypes CD38− CD34++ and CD38+ CD34++ , respectively. We also describe a method for the growth of colony-forming cells (CFCs) from these cell
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