- ￥1521
- 华韵生物(Huayunbio)
- HFC1647-25μg
- 2025年07月15日
- FCM
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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
12个月
- 供应商：
广州华韵生物科技有限公司
- 应用范围：
FCM
- 规格：
25μg
请联系华韵客服获取说明书。
产品简介：
| Background |
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
|
| Alternate Names |
Activation B7-2 antigen;Cd86;ETC-1;Early T-cell costimulatory molecule 1;T-lymphocyte activation antigen CD86
|
| Swissprot |
P42082
|
| Gene ID |
12524
|
| Clone No |
GL-1
|
| Host |
Rat
|
| Reactivity |
Mouse
|
| Application |
FCM
|
| Isotype |
Rat IgG2a, κ
|
| Isotype Control |
APC Rat IgG2a, κ Isotype Control[2A3]
|
| Conjugation |
APC
|
| Conjugation Information |
APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
|
| Spectrum |
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献和实验Stimulation of Anti-HIV-1 Cytotoxic T Lymphocytes by Dendritic Cells
Dendritic cells (DC) are highly specialized antigen-presenting cells (APC) in both primary and secondary T-cell responses. This may be related to their expression of high levels of MHC class I and II antigens (1 -4 ), costimulatory
Diego, CA); GSK-3α (Upstate, LakePlacid, NY); and b-actin (Sigma, St. Louis, MO). 7. Secondary antibodies: anti-mouse and anti-rabbit IgG conjugatedto horseradish peroxidase (Santa Cruz Biotechnology,Santa Cruz, CA). 8. Enhanced chemiluminescent
v468 Chapter 6 细胞内结肠腺瘤样息肉蛋白核定位以及细胞质检测
: anti-mouse or anti-rabbit conjugated tobiotin from Dako Corp. (Glostrup, Denmark) diluted 1:500. 8. Third antibody: Texas Red conjugated to avidin from VectorLaboratories (Burlingame, CA) diluted 1:500. 9. Nuclear stain: 0.05 μg/mL of Hoechst
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