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文献和实验diabetic mouse model. Furthermore, the detection of peripheral autoreactive CD8+ T cells in this mouse model is indicative of beta cell killing and correlates with the development of diabetes. We describe two protocols that are helpful for the detection
Pathways Implicated in Stem Cell Migration: The SDF-1/CXCR4 Axis
The hallmark of hematopoietic stem and progenitor cells (HSPCs) is their motility, which is essential for their function, such as recruitment upon demand. Stromal Derived Factor-1 (SDF-1, CXCL12) and its major receptor CXCR4 play major roles
Mouse ES Cell-Derived Hematopoietic Progenitor Cells
before any clinical applications. The ability of these cells to engraft is dependent on their expression of cell surface markers which guide their homing patterns. In this review, I discuss murine hematopoietic progenitor cells derived from mouse ES cells. Stem cells
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