- ￥26782
- Merck
- SCC297
- 2026年01月21日
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细胞名称：N2A Psen1/Psen2 Double Knockout Mouse Neuroblastoma Cell Line
货号：SCC297
规格：1X10⁶ cells
应用：Each vial contains >1X106 viable cells.
特点和优势：The N2A Psen1/2 cell line is a unique tool for the assessment of the contribution of PSEN mutations to AD pathology and widens the path to targeted therapies for AD and related neurodegenerative diseases.
储存及稳定性：Cells should be stored in liquid nitrogen until use. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.
其他说明：This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation.
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文献和实验Generation of Double-Knockout Embryonic Stem Cells
(1 ). Inbreeding of heterozygous animals will yield offspring carrying the disruption in both alleles. The phenotypic consequences of a complete gene knockout in the mouse germ line can provide pivotal information on the function of the gene in development
Characterization and Validation of Cre‐Driver Mouse Lines
) and the CreERT2 gene. (B ) RXRαΔAF2(LNL) mouse line. This line is used as a floxed reporter line for determination of Cre recombinase activity by qPCR. A floxed Neo cassette is inserted between exon 9 and 10 of the RXRα gene, and a mutation (*) is present in exon
Developing Genetically Engineered Mouse Models to Study Tumor Suppression
Costantini, F. and Lacy, E. 1981. Introduction of a rabbit beta‐globin gene into the mouse germ line. Nature 294:92‐94. Cui, X., Ji, D., Fisher, D.A., Wu, Y
