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文献和实验Challenges and Opportunities in Fractionation of Recombinant Human Mannan-Binding Lectin
Mannan-binding lectin is an oligomeric protein of the innate immune system. Both natural MBL as well as recombinant protein is a heterogeneous composition of oligomers containing from two up to at least eight structural units. Recombinant
Inhibition of HIV Infection by Lectin Binding to CD4
target to block infection. One of the first events in the infection of T-cells by the human immunodeficiency virus (HIV) is the binding of the viral envelope glycoprotein gp120 to the differentiation antigen CD4 expressed on the host cell
Inhibition of HIV Infection by Lectin Binding to gp120
Human immunodeficiency virus (HIV) is the causative agent of AIDS (acquired immunodeficiency syndrome). The polypeptide precursor gp160 of HIV-1 forms the external glycoprotein, gp120 and the transmembrane glycoprotein, gp41 (1 ). Sequence
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