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文献和实验the intracellular mechanisms required for hESC maintenance. This chapter describes the serum-free maintenance of hESC in culture by addition of sphingosine-1-phosphate (S1P) and platelet-derived growth factor (PDGF). This complete protocol provides a chemically
Secretion of Recombinant Human Insulin-Like Growth Factor I (IGF-I)
The development of efficient recombinant protein production processes can be a critical factor in whether or not a pharmaceutical therapeutic protein can enter human clinical trials and ultimately the marketplace. This is especially true
Ribozyme Targeting of the Growth Factor Pleiotrophin
57399) for melanoma angiogenesis and metastasis. PTN is a secreted polypeptide growth factor (3 ) that is expressed in a variety of established tumor cell lines and primary human tumor specimens (4 ), is a mitogen for fibroblasts (3 ), epithelial
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