大鼠 HSF1 (Heat Shock Factor 1)

Isolation and Characterization of the Heat Shock RNA 1

of a set of cytoprotective genes. Most of the induction occurs at the level of transcription. The master regulator, heat shock transcription factor (HSF, or HSF1 in vertebrates), is responsible for the induction of HS gene transcription in response

Targeted Deletion of Hsf1, 2, and 4 Genes in Mice

Heat-shock transcription factors (Hsfs) regulate transcription of heat-shock proteins as well as other genes whose promoters contain heat-shock elements. There are at least five Hsfs in mammalian cells, Hsf1, Hsf2, Hsf3, Hsf4, and Hsfy

大鼠痛觉模型制作

领取SD雄性大鼠，体重200-220g为宜试验前测试痛阈（我们用的是意大利Ugobasile的heat-flux meter测痛仪， 国 产的功能也不差），痛阈极端大/小的最好挑除不用试验前至少3天每日早晨9点－9点半，将大鼠放入观察笼中适应环境试验时用微量注射器抽取100-200ul甲醛（浓度自己定）于大鼠下肢脚掌皮内注射，注射后留置针头约30－60sec,放大鼠入笼，摄像，人员全部离开（非常重要！）以其抬足和舔舐足掌为指标记录相关数据大鼠的饲养时要勤换垫料（最好每天换），有鼠便溏稀时要及时