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文献和实验Measuring Interferon Alpha and Other Cytokines in SLE
The progression of disease in patients with systemic lupus erythematosus (SLE) is affected by production, accumulation, and actions of cytokines. Type I interferon (IFN), specifically IFN-α, is recognized as a central mediator of disease
Protein Engineering of Interferon Alphas
Interferon (IFN)-αs constitute a family of proteins exhibiting high degree of homology in primary, secondary, and tertiary structure and display a high level of species specificity in their biological properties. However, small structural
Transfection of Mller Cells With Type I Interferon Transgenes: Resistance to HSV-1 Infection
Gene transfer is a widely used experimental approach to determine the value of specific genes under a variety of conditions. This chapter focuses on the expression of two human antiviral genes, interferon (IFN)-α2 and IFN-β, driven
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