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文献和实验Multimeric Analysis of von Willebrand Factor
Von Willebrand Factor (vWF) in normal plasma is composed of a series of high molecular multimers, ranging in size from 8�105 to over 15�106 Daltons (1 ). The multimeric structure of vWF was first investigated by two-dimensional crossed
Screening for Candidate Mutations Causing von Willebrands Disease (vWD)
von Willebrand factor (vWF) is a large, complex glycoprotein that exists in plasma and platelets, and is synthesized by megakaryocytes and endothelial cells. vWF plays an essential role in hemostasis in at least two ways. It is involved
-Duistermaat j.j,et.al. Familial clustering of factor Ⅷ and von Willebrand Factor levels , Thromb Haemost 1998,79:323-7 2.O , Donnell J,Mumford A.D,Manning R,A,Elevation of F Ⅷ :C in venous thrombembolism is persistent and independent of the Axute
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