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文献和实验Methods for the Detection of D-Amino-Acid Oxidase
that the mouse does not have this enzyme in its liver (13 ). The mouse is a very unique animal in this respect. Northern hybridization, RT-PCR, and western blotting gave positive results for the presence of D-amino-acid oxidase in the ddY/DAO- mice (12 , 17
Methods for the Detection of D-Amino-Acid Oxidase
-PCR, and western blotting gave positive results for the presence of D-amino-acid oxidase in the ddY/DAO- mice ( 12 , 17 ). However, the kidney and brain homogenates of these mice did not show D-amino-acid oxidase activity ( 18 , 19 ). Therefore, we concluded
Histamine N-Methyltransferase: Enzymology and Functional Aspects
, HNMT has not been the subject of a comprehensive review or analysis. This is surprising since HNMT and diamine oxidase (DAO; EC 1.3.4.6) are the only known enzymes that terminate the physiologic activity of histamine (HA) in mammals. However, to a large
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