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文献和实验一、什么是外泌体? 外泌体(Exosomes)是大小为 30-150 nm、呈茶托状的细胞外囊泡(Extracellular vesicles, EVs),广泛存在于细胞培养上清及各种体液中,包括血液、淋巴液、唾液、尿液、精液、乳汁等。 几乎所有细胞都可以分泌外泌体,但是外泌体来源不同,其内部装载的 RNA、蛋白质、脂类等重要物质在数量和丰度上有很大差异。 二、外泌体的作用和功能 外泌
Detecting Low‐Affinity Extracellular Protein Interactions Using Protein Microarrays
extracellular protein interactions are critical for cellular recognition processes, but are not generally detected by methods that can be applied in a high?throughput manner. This unit describes a protein microarray platform that significantly improves
) or early death. The serine protease uPA, in concert with its inhibitor PAI-1, promotes tumor cell adhesion, migration, and proliferation, as well as extracellular matrix degradation and, thus, facilitates tumor cell invasion and metastasis. The various
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