- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- PME46664
- 2025年07月10日
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- 详细信息
- 技术资料
- 保存条件：
-80°C
- 保质期：
请咨询
- 英文名：
Human p27 KIP 1 (CDKN1B) (NM_004064) Protein
- 库存：
1 week
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
20 ug
| 产品类别 | ECD Proteins |
|---|---|
| 靶点 | p27 KIP 1 |
| Uniprot ID | P46527 |
| 背景 | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014] |
| 描述 | Recombinant protein of human cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B), full length, with C-terminal DDK tag, expressed in sf9, 20ug |
| 分子量 | 22.1 kDa |
| 纯度 | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| 别名 | CDKN4; KIP1; MEN1B; MEN4; P27KIP1 |
| 标签 | C-DDK |
| 表达宿主 | Sf9 |
| 组分与重悬 | 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol |
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Human p27 KIP 1 (CDKN1B) (NM_004064) Protein
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