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- DIMA BIOTECH/缔码生物
- 武汉
- PME101702
- 2025年11月27日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 保质期：
12个月
- 英文名：
Recombinant human 4-1BB(87-118) Protein with C-terminal human Fc tag
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
10μg/50μg/100μg
| 规格： | 10μg | 产品价格： | ￥909.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥3333.0 |
| 规格： | 100μg | 产品价格： | ￥4999.0 |
| 产品类型 | ECD Proteins |
|---|---|
| 靶点 | 4-1BB |
| Uniprot ID | Q07011 |
| 别名 | ILA; TNFRSF9; CD137; CDw137; IMD109 |
| 背景 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008] |
| 产品英文名称 | Recombinant human 4-1BB(87-118) Protein with C-terminal human Fc tag |
| 分子结构 | 4-1BB(Asp87-Lys118) hFc(Glu99-Ala330) |
| 分子量 | The protein has a predicted molecular mass of 29.5 kDa after removal of the signal peptide. The apparent molecular mass of 4-1BB(87-118)-hFc is approximately 25-35 kDa due to glycosylation. |
| 纯度 | The purity of the protein is greater than 90% as determined by SDS-PAGE and Coomassie blue staining. |
| 标签 | C-Human Fc tag |
| 有无偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 货期 | In Stock |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 应用范围 | Research use only |
Figure 1. Human 4-1BB(87-118) Protein, hFc Tag on SDS-PAGE under reducing condition.
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Identifying Small‐Molecule Modulators of Protein‐Protein Interactions
interactions. Nat. Biotechnol. 18:847‐851. Ramani, A.K., Bunescu, R.C., Mooney, R.J., and Marcotte, E.M. 2005. Consolidating the set of known human protein‐protein interactions
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