- ￥690 - 3699
- DIMA BIOTECH/缔码生物
- 武汉
- PME101386
- 2025年11月27日
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- 详细信息
- 技术资料
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 保质期：
12个月
- 英文名：
Recombinant human ITGAV protein with C-terminal 6×His tag and human ITGB6 protein with C-terminal human Fc tag
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
10μg/50μg/100μg
| 规格： | 10μg | 产品价格： | ￥690.0 |
|---|---|---|---|
| 规格： | 50μg | 产品价格： | ￥2500.0 |
| 规格： | 100μg | 产品价格： | ￥3699.0 |
| 产品类型 | ECD Proteins |
|---|---|
| 靶点 | ITGAV and ITGB6 |
| Uniprot ID | P06756 and P18564 |
| 别名 | CD51; MSK8; VNRA; VTNR and AI1H |
| 背景 | Integrin alpha V beta 6 is a heterodimer of beta-6 associating with alpha-V. Integrin alpha-V beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. Also, Integrin alpha-V beta-6 acts as a receptor for coxsackievirus A9 and coxsackievirus B1 as well as herpes simplex virus-1/HHV-1. Furthermore, it binds the TGF-beta latency‑associated peptide (LAP) and activates TGF-beta 1 or TGF-beta 3 from large latent complexes. This activation requires interaction with LTBP-1 and fibronectin, and is enhanced by PAR-1. |
| 产品英文名称 | Recombinant human ITGAV protein with C-terminal 6×His tag and human ITGB6 protein with C-terminal human Fc tag |
| 分子结构 | ITGAV(Phe31-Val992) 6×His tag and ITGB6(Gly22-Asn707) hFc(Glu99-Ala330) |
| 分子量 | The protein has a predicted molecular mass of 107.1 and 100.4 kDa after removal of the signal peptide. The apparent molecular mass of ITGAV-His abd ITGB6-hFc is approximately 130-250 kDa due to glycosylation. |
| 纯度 | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| 标签 | C-6×His tag and C-Human Fc tag |
| 有无偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| 货期 | In Stock |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 应用范围 | Research use only |
Figure 1. Human ITGAV and ITGB6 Protein, His and hFc Tag on SDS-PAGE under reducing condition.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
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人ITGAV and ITGB6重组蛋白/Human ITGAV and ITGB6 Heterodimer Protein, His Tag and hFc Tag
￥690 - 3699
