KCNH2全长蛋白/Human KCNH2-Strep fu

货号	FLP120501
产品分类	Full Length Transmembrane Proteins
价格&规格	Price: 10 μg ￥5670.00 ;50 μg ￥27000.00 ; 100 μg ￥49500.00
背景	A voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2).
描述	Human KCNH2-Strep full length protein-synthetic nanodisc
分子量	The human full length KCNH2-Strep protein has a MW of 126.7 kDa
蛋白家族	Druggable Genome, Ion Channels: Potassium, Transcription Factors, Transmembrane
信号通路	N/A
别名	ERG-1; ERG1; H-ERG; HERG; HERG1; Kv11.1; LQT2; SQT1
标签	C-Flag&Strep Tag
是否偶联	Unconjugated
表达宿主	HEK293
形式	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
靶点	KCNH2
Uniprot ID	Q12809
用途	Research use only

验证图

Figure 1. Elisa plates were pre-coated with C-Flag&Strep Tag KCNH2-Strep-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with KCNH2-Strep-nanodisc is 2.328ng/ml.



Figure 2. Human KCNH2-Strep-Nanodisc, C-Flag&Strep Tag on SDS-PAGE