- 询价
- DIMA BIOTECH/缔码生物
- 武汉
- FLP100498
- 2025年10月30日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20°C to -80°C
- 保质期：
12个月
- 英文名：
Human SCAP full length protein-synthetic nanodisc
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 规格：
10μg
| 货号 | FLP100498 |
|---|---|
| 产品分类 | Full Length Transmembrane Proteins |
| 价格&规格 | Price: 10 μg ￥6300.00 ; 50 μg ￥30000.00 ; 100 μg ￥55000.00 |
| 背景 | A protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. |
| 描述 | Human SCAP full length protein-synthetic nanodisc |
| 分子量 | The human full length SCAP protein has a MW of 139.7 kDa |
| 蛋白家族 | Druggable Genome, Transcription Factors, Transmembrane |
| 信号通路 | N/A |
| 别名 | N/A |
| 标签 | C-Flag Tag |
| 是否偶联 | Unconjugated |
| 表达宿主 | HEK293 |
| 形式 | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| 靶点 | SCAP |
| Uniprot ID | Q12770 |
| 用途 | Research use only |
验证图
Figure 1. Elisa plates were pre-coated with Flag Tag SCAP-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with SCAP-Nanodisc is 5.795ng/ml.
Figure 2. Human SCAP-Nanodisc, Flag Tag on SDS-PAGE
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Immunity：北大蒋争凡课题组发现 STING 后高尔基体囊泡转运的重要性及机制
Immunity 上以 research article 形式在线发表了 ARMH3-mediated recruitment of PI4KB directs Golgi-to-endosome trafficking and activation of the antiviral effector STING，报道了 ARMH3 作为接头蛋白招募 PI4KB 到 STING，PI4KB 通过合成 PI4P 促进 STING 从高尔基体到内体的转运（Golgi-to-endosome trafficking
三句话读懂一篇 CNS：晚睡晚起导致抑郁；吃药代替运动健身；高脂肪饮食引发结直肠癌...
结构 研究表明 LRRK2 蛋白酶突变是导致帕金森病的关键原因之一。 2021 年 6 月 8 日，圣裘德儿童研究医院孙吉教授团队在 Cell 上发表研究论文 Structural analysis of the full-length human LRRK2，该研究首次解析了人类 LRRK2 全长蛋白的高分辨率结构，为人类战胜帕金森病提供了理论参考。图 6：来源 Cell 7. Lacent: 父母学历越高，所生小孩死亡率越低 2021 年 6 月 10 日，挪威科技大学 Terje
receptor8. Mouse apoB is a large protein of 4,515 amino acids and is expressed predominantly in liver and jejunum. apoB mRNA is subject to post-transcriptional editing, and the unedited and edited transcripts encode the full-length protein apoB-100
技术资料暂无技术资料 索取技术资料
