Human FGγ (Fibrinogen Gamma ch

Development of Novel Major Histocompatibility Complex Class I and Class II-Deficient NOD-SCID IL2R Gamma Chain Knockout Mice for Modeling Human Xenoge

) and recombination activating 1 or 2 gene (Rag1 or Rag2 ) knockout mice bearing a targeted mutation in the gene encoding the IL2 receptor gamma chain (IL2rγ ) have been reported. The addition of the mutated IL2rγ gene onto an immunodeficient mouse stock facilitates

ELISA 中的抗原与抗体的反应

抗体的结构 抗体是能与抗原特异性结合的免疫球蛋白(immunoglobulin,Ig)。Ig 分五类，即 IgG、IgA、IgM、IgD 和 IgE。与免疫测定有关的 Ig 主要为 IgG 和 IgM。Ig 由两个轻链（L）和两个重链（H）的单体组成。Ig 的轻链是相同的，有 κ（kappa）和 λ（Lambda）两种型别。五类 Ig 的重链结构不同，这决定了它们的抗原性也不同。IgG 和 IgM 的重链分别称为 γ（gamma）链和 μ（mu ）链。 重链和轻链的 N 端的氨基酸排列顺序

Production of Chimeric Heavy-Chain Antibodies

of fragment crystallizable (Fc), which is known to be crucial for a long serum half-life through binding to FcRn and antibody-mediated cell killing through binding to Fcγ receptors and complement. Single-domain antibodies (sdAbs) derived from camelid heavy