- 询价
- 辰辉创聚生物
- 中国
- NBAB-103216
- 2025年07月12日
- WB; IHC-P
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthetic phosphopeptide corresponding to residues around Ser317 of human Chk1.
- 亚型：
Monoclonal Rabbit IgG
- 保存条件：
This liquid antibody can be stored at 2℃-3098℃ for at least two weeks. Avoid repeated freeze/thaw cycles.
- 克隆性：
单克隆
- 适应物种：
Human
- 保质期：
see COA
- 库存：
大量
- 供应商：
辰辉创聚生物
- 应用范围：
WB; IHC-P
- 靶点：
Phospho-Chk1 (Ser317)
- 抗体英文名：
Phospho-Chk1 (Ser317) antibody
- 抗体名：
Phospho-Chk1 (Ser317)抗体
- 规格：
100ug;500ug;1mg
| 产品信息
品名:NebuSelect™ Phospho-Chk1 (Ser317) Monoclonal Antibody
货号:NBAB-103216
品牌:Nebulabio
规格:100ug;500ug;1mg
| 产品描述
| 产品属性
Product Category：Rabbit MAb
Reactivity：Human
Specificity：Human Phospho-Chk1 (Ser317)
Immunogen：A synthetic phosphopeptide corresponding to residues around Ser317 of human Chk1.
Isotype：Monoclonal Rabbit IgG
Purification：Protein A
Buffer：10 mM HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
Conjugate：Unconjugated
Applications：WB; IHC-P
Dilution：WB: 1:1000-1:2000 IHC-P: 1:500-1:2000
Storage：Store at 4°C for short-term, -20°C for long-term. Avoid repeated freezing and thawing cycles.
For Research Use Only!
To get more information, please contact us freely.
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文献和实验Mammalian CHK1 is a Ser/Thr effector kinase that plays critical roles in the DNA damage-activated cell cycle checkpoint signaling pathway downstream of ATR (ATM and Rad3-related protein kinase). This chapter is focused on describing an assay
Methods for Studying Checkpoint Kinases Chk1
-terminal regulatory domain. Within the regulatory domain there are two residues, Serine-317 (S317) and Serine-345 (S345), which are phosphorylated in active Chk1 molecules, and subsequently dephosphorylated to inactivate Chk1 and allow mitotic entry
throughout interphase but not in mitosis. The primary site for phosphorylation of cdc25 is at Ser216. Phosphorylated cdc25 binds to members of the 14-3-3 family of proteins which prevents its activation of cdc2. Chk1, a protein kinase involved in the DNA damage
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