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- 详细信息
- 文献和实验
- 技术资料
- 库存:
100
- 供应商:
南京赛泓瑞
- 应用:
酶联法样本检测
- 适应物种:
人/大鼠/小鼠等各类物种
- 样本:
血清 细胞等
- 规格:
48T/96T
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文献和实验Determination of NOS Activity Using Cyclic-GMP Formation
guanosine 3′,5′-cyclic monophosphate (cGMP) (1 ). GC-S contains heme as a prosthetic group, and NO apparently binds to the heme moiety and induces a conformational change in the enzyme which either dis-inhibits or activates the catalytic site
The Analysis and Assay of Cyclic Nucleotide Phosphodiesterase Isoenzyme Activity
are inactivated by a large group of enzymes collectively known as 3′,5′-cyclic nucleotide phosphodiesterases (PDEs; EC 3.1.4.17), which catalyze the hydrolytic cleavage of the 3′ phosphodiesterase bond to form the corresponding 5′ nucleotide (i.e., 5′AMP or 5′GMP
Cyclic nucleotide phosphodiesterases (PDE s) include a large group of structurally related enzymes that are responsible for the hydrolysis of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). These enzymes
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