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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Short term 4℃; Long term -20℃.
- 保质期:
见COA
- 英文名:
Recombinant Human Tau, 1-441aa, His-tag
- 库存:
大量
- 供应商:
北京辰辉创聚生物技术有限公司
- 规格:
100ug;1mg;Bulk

| 产品信息
品名:NebuSelect™ Recombinant Human Tau, 1-441aa, His-tag
货号:NBL-250947
品牌:Nebulabio
规格:100ug;1mg;Bulk
| 产品描述
| 产品属性
Alias/Synonyms:TAU; TAU; DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; Microtubule-associated protein tau
Species:Human
Expression System:HEK293
Accession:P10636-8
Residues:1-441 aa
Tags:C-His tag
Molecular Weight:65-80 kDa
Target Name: Tau
Purity:> 95%
Formulation:Freeze-dried powder
Bioactivity:Testing in progress
Endotoxin:see COA
Application:Immunogen; SDS-PAGE; WB
For Research Use Only!
To get more information, please contact us freely.
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文献和实验Cell-Based Assays for Regulators of Tau Biology
portray this cellular landscape. While we cannot ask many mechanistic questions using the human brain as our test subject, cell culture techniques that have emerged at least provide us with the ability to pose fundamental biochemical questions
Methods for Studying Interferon Tau Stimulated Genes
epithelium. Recent experiments have used human 2fTGH and U3A (Stat1 null) cells to determine the IFNτ signaling pathway and discover ISGs regulated by IFNτ using transcriptional profiling. Given that ISGs are increased in the endometrium during pregnancy
,并维持其稳定性。它的微管结合能力由翻译后修饰来控制,其中磷酸化修饰是主要方式之一,正常情况下磷酸化修饰的水平较低,而过度磷酸化则会导致 Tau 蛋白失活,无法集结微管蛋白,致使神经细胞变性。由于 Tau 蛋白有多个磷酸化位点,并且参与调节的蛋白激酶和磷酸酯酶又不止一种,所以这使得 AD 的发病机制非常复杂。成人大脑中有 6 种 Tau 蛋白亚型,其中三种是有三段微管结合重复区域 (3R-tau),另三种是有四段微管结合重复区域(4R-tau)。Tau 全长蛋白被记做 2N4R 或 Tau-441
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