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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
冷冻-20℃
- 保质期：
咨询
- 英文名：
H3R antagonist 1
- 库存：
100+
- 供应商：
上海维亦特生物科技有限公司
- CAS号：
1448422-61-4
分子量：341.4
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文献和实验Characterization of Histaminergic Receptors
for receptor (nM) Specific activity (Ci/mmol) Nonspecific binding Signal‐to‐noise ratio Source Comments H 1 Receptor [3 H]Mepyramine Antagonist
for the treatment of SCLC (1 ,2) . Although antagonist G blocks SCLC cell growth (IC50 = 24.5 � 1.5 and 38.5 � 1.5 μM for the H69 and H510 cell lines, respectively), its exact mechanism of action is unclear. Factors affecting the balance between SCLC cell
with the test-tube radioligand binding assay. In this assay, a radiolabeled ligand (labeled with 125 I or 3 H, for example) is incubated with a membrane preparation or cells in presence of receptor subtype-specific antagonist or agonist. After reaching
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