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- 文献和实验
- 技术资料
- 保存条件：
冷冻-20℃
- 保质期：
咨询
- 英文名：
FLT3 kinase inhibitor 2HCl
- 库存：
100+
- 供应商：
上海维亦特生物科技有限公司
- CAS号：
2411178-94-2
分子式：C25H29Cl2N7O2
分子量：530.449
溶解度：
DMSO: 50 mg/mL (94.26 mM),
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文献和实验Kinase Inhibitor Profiling Using Chemoproteomics
Quantitative chemoproteomics has recently emerged as an experimental approach to determine protein interaction profiles of small molecules in a given cell line or tissue. In contrast to standard biochemical and biophysical kinase assays
Kinase Inhibitor Selectivity Profiling Using Differential Scanning Fluorimetry
and widely used approach is the direct measurement of the effect of the added ligands on its activity. A variety of enzymatic assay formats have been successfully applied for inhibitor screening of protein kinases. However, enzymatic assays require an active
FLT3 Mutations in Acute Myeloid Leukemia
The prevalence of an internal tandem duplication (ITD) of the juxtamembrane domain-coding sequence and a missense mutation of D835 within the kinase domain of the FLT3 gene is 15–35% and 5–10% of adults with acute myeloid leukemia (AML
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