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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
冷冻-20℃
- 保质期:
咨询
- 英文名:
Collagen proline hydroxylase inhibitor-1
- 库存:
100+
- 供应商:
上海维亦特生物科技有限公司
- CAS号:
223663-32-9
分子式:C24H21N5O4
分子量:443.45
溶解度:
DMSO: Slightly soluble
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文献和实验Recombinant Collagen Trimers from Insect Cells and Yeast
in the synthesis of all collagens, as 4-hydroxyproline-deficient collagen polypeptide chains cannot form triple helices that are stable at 37�C (5 ,6 ). All attempts to assemble an active prolyl 4-hydroxylase tetramer from its subunits in vitro
. The methods are based on the incorporation of radiolabeled proline into collagen as hydroxyproline and its measurement in intact protein and collagen breakdown products. In addition, an accurate and highly sensitive high-performance liquid chromatography
(Table 1 ). The enzymatic activity of MMP family members is controlled by a group of inhibitor proteins known as the Tissue Inhibitors of Metalloproteinases (TIMPs), which consist of four family members (Table 2 ). Whereas all four TIMPs can inhibit
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