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- 文献和实验
- 技术资料
- 保存条件:
冷冻-20℃
- 保质期:
咨询
- 英文名:
CB1 antagonist 2
- 库存:
100+
- 供应商:
上海维亦特生物科技有限公司
- CAS号:
614726-85-1
分子式:C17H12Cl3N3O
分子量:380.66
别名: AM4113
溶解度:
DMSO: 1.9 mg/mL (4.99 mM),
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文献和实验Methods Evaluating Cannabinoid and Endocannabinoid Effects on Gastrointestinal Functions
(Δ9 -THC) and well-studied representatives of other classes of exogenous cannabinoid CB1 /CB2 receptor agonists inhibit gastrointestinal motility, peristalsis, defecation, and secretions via cannabinoid CB1 receptors since the CB1 (SR141716
Overview of Receptor Allosterism
Figure 1.21.2 Effect of: (A ) negative allosteric modulator, (B ) positive allosteric modulator, or (C ) a competitive antagonist on orthosteric ligand‐receptor occupancy (ρA ). For all the simulations, p K
or competitive antagonist that binds to the endogenous agonist binding site. Because of the complex nature of allosteric phenomena, the detection and quantification of their effects on orthosteric ligand binding relies on the use of both equilibrium and non
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