- 询价
- 辰辉创聚生物
- 中国
- NBL-242805
- 2025年07月15日
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- 详细信息
- 技术资料
- 保存条件：
Short term 4℃; Long term -20℃.
- 保质期：
见COA
- 英文名：
Recombinant Human MDL-1/CLEC5A, hFc-tag
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug;1mg;Bulk
| 产品信息
品名:NebuSelect™ Recombinant Human MDL-1/CLEC5A, hFc-tag
货号:NBL-242805
品牌:Nebulabio
规格:100ug；1mg；Bulk
| 产品描述
NebuSelect™ Recombinant Human MDL-1/CLEC5A, hFc-tag(Cat#NBL-242805) is expressed in HEK293 with hFc tag at the N-Terminus.It contains Tyr26-Lys188.
| 产品属性
表达系统:HEK293
标签:hFc-tag
靶点名称:MDL-1/CLEC5A
物种：Human
分子量：The protein has a predicted MW of 46 kDa. Due to glycosylation, the protein migrates to 63-70 kDa based on Bis-Tris PAGE result.
氨基酸序列：
Accession: Q9NY25-1
纯度:＞95%
内毒素：＜1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
In C. elegans, increased lifespan in daf-2 insulin/IGF-1 receptor mutants is accompanied by up-regulation of the MDL-1 Mad basic helix-loop-helix leucine zipper transcription factor.MDL-1, like its mammalian orthologs, is an inhibitor of cell proliferation and growth that slows progression of an age-related pathology in C. elegans (uterine tumors). In addition, intestine-limited rescue of mdl-1 increased lifespan but not to wild type levels. Thus, mdl-1 likely acts both in the intestine and the germline to influence age-related mortality.
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