Spike RBD (N501Y)蛋白 | SARS-COV

| 产品信息

品名:NebuSelect™ Recombinant SARS-COV-2 Spike RBD (N501Y), His-tag

货号:NBL-242796

品牌:Nebulabio

规格:100ug；1mg；Bulk

| 产品描述

NebuSelect™ Recombinant SARS-COV-2 Spike RBD (N501Y), His-tag(Cat#NBL-242796) is expressed in HEK293 with His tag at the C-Terminus.It contains Arg319-Phe541(N501Y).

| 产品属性

表达系统:HEK293

标签:His-tag

靶点名称:Spike RBD (N501Y)

物种：SARS-COV-2

分子量：The protein has a predicted MW of 26.2 kDa. Due to glycosylation, the protein migrates to 36-40 kDa based on Bis-Tris PAGE result.

氨基酸序列：

Accession: QHD43416.1

纯度:＞95%

内毒素：＜1EU/ug(LAL Method)

储存运输条件: Short term 4℃; Long term -20℃.

| 靶点信息

The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.

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