CRTAM蛋白 | Cynomolgus CRTAM, hF

| 产品信息

品名:NebuSelect™ Recombinant Cynomolgus CRTAM, hFc-tag

货号:NBL-242771

品牌:Nebulabio

规格:100ug；1mg；Bulk

| 产品描述

NebuSelect™ Recombinant Cynomolgus CRTAM, hFc-tag(Cat#NBL-242771) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Ser18-Gly287.

| 产品属性

表达系统:HEK293

标签:hFc-tag

靶点名称:CRTAM

物种：Cynomolgus

分子量：The protein has a predicted MW of 56.6 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.

氨基酸序列：

Accession: XP_005580021.1

纯度:＞95%

内毒素：＜1EU/ug(LAL Method)

储存运输条件: Short term 4℃; Long term -20℃.

| 靶点信息

Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

For Research Use Only!

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