- 询价
- 辰辉创聚生物
- 中国
- NBL-242530
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Short term 4℃; Long term -20℃.
- 保质期：
见COA
- 英文名：
Recombinant Human IFN gamma R1/IFNGR1, hFc-tag
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug;1mg;Bulk
| 产品信息
品名:NebuSelect™ Recombinant Human IFN gamma R1/IFNGR1, hFc-tag
货号:NBL-242530
品牌:Nebulabio
规格:100ug；1mg；Bulk
| 产品描述
NebuSelect™ Recombinant Human IFN gamma R1/IFNGR1, hFc-tag(Cat#NBL-242530) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Glu18-Gly245.
| 产品属性
表达系统:HEK293
标签:hFc-tag
靶点名称:IFN gamma R1/IFNGR1
物种：Human
分子量：The protein has a predicted MW of 52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
氨基酸序列：
Accession: AAH05333
纯度:＞95%
内毒素：＜1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.
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文献和实验Assessment of Natural Killer Cell Responses to Human Cytomegalovirus-Infected Macrophages
. Herein, we describe an autologous assay system to assess NK cell responses to HCMV-infected macrophages which is based on flow cytometry to detect CD107a expression and interferon gamma (IFNγ) secretion. Further we established a simple method to handle HCMV-infected macrophages
Combining ELISPOT and ELISA to Measure Amounts of Cytokines Secreted by a Single Cell
assays and developed a protocol to calculate the amount of IFN gamma secreted by each cell. A suspension of human peripheral blood mononuclear cells was split into two pools and cells from one pool were cultured in a regular ELISPOT plate, whereas cells
tumor necrosis factor–{alpha} (TNF-{alpha}), interferon-beta (IFN-beta), and IFN-{gamma} (1). The authors observed that of ~200 miRNAs examined, only miR-155 increased in amount in response to both TLR ligands and IFN-beta. miR-155 accumulated
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