- 询价
- 辰辉创聚生物
- 中国
- NBL-242415
- 2025年07月12日
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- 详细信息
- 技术资料
- 保存条件：
Short term 4℃; Long term -20℃.
- 保质期：
见COA
- 英文名：
Recombinant Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer, His-tag
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug;1mg;Bulk
| 产品信息
品名:NebuSelect™ Recombinant Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer, His-tag
货号:NBL-242415
品牌:Nebulabio
规格:100ug；1mg；Bulk
| 产品描述
NebuSelect™ Recombinant Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer, His-tag(Cat#NBL-242415) is expressed in HEK293 with His tag at the C-Terminus.It contains Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail.
| 产品属性
表达系统:HEK293
标签:His-tag
靶点名称:Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer
物种：Mouse
分子量：The protein has a predicted MW of 126.60 kDa(ITGA2)&82.80 kDa(ITGB1). Due to glycosylation, the protein migrates to 128-138 kDa(ITGA2)&105-115 kDa(ITGB1) based on Bis-Tris PAGE result.
氨基酸序列：Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail
Accession: Q62469(ITGA2)&P09055-1(ITGB1)
纯度:＞95%
内毒素：＜1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression.HOS cells normally lacking alpha 2 beta 1 integrin were forced to express it, and this prevented the down-regulation in the levels of alpha 1 (I) collagen mRNA when cells were grown inside collagen gels. The data indicate that the level of MMP-1 expression is regulated by the collagen receptor alpha 2 beta 1 integrin.
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