Siglec-10蛋白 | Biotinylated Hum

| 产品信息

品名:NebuSelect™ Recombinant Biotinylated Human Siglec-10, Avi-hFc-tag

货号:NBL-242100

品牌:Nebulabio

规格:100ug；1mg；Bulk

| 产品描述

NebuSelect™ Recombinant Biotinylated Human Siglec-10, Avi-hFc-tag(Cat#NBL-242100) is expressed in HEK293 with hFc tag and Avi tag at the C-Terminus.It contains Met17-Thr546.

| 产品属性

表达系统:HEK293

标签:Avi-hFc-tag

靶点名称:Siglec-10

物种：Human

分子量：The protein has a predicted MW of 85.8 kDa. Due to glycosylation, the protein migrates to 95-110 kDa based on Bis-Tris PAGE result.

氨基酸序列：Met17-Thr546

Accession: Q96LC7-1

纯度:＞95%

内毒素：＜1EU/ug(LAL Method)

储存运输条件: Short term 4℃; Long term -20℃.

| 靶点信息

Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.

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