Anti-PSD95, clone K28/43-L, Re

PSD95 (Postsynaptic Density Protein 95) is a critical scaffolding protein located in the postsynaptic terminals of neurons. It plays a central role in organizing the postsynaptic density, which is a protein-rich structure responsible for the clustering of neurotransmitter receptors, ion channels, and signaling molecules. PSD95 interacts with a variety of proteins, including NMDA receptors, AMPA receptors, and other signaling molecules, to regulate synaptic function and plasticity. It is involved in processes like synaptic signaling, synaptogenesis, and long-term potentiation (LTP), which are essential for learning, memory, and neuronal communication. Dysregulation of PSD95 has been implicated in various neurological disorders, including schizophrenia, autism, and intellectual disabilities, making it a key target for research in neuroscience.