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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
Mouse / IgG1
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
EMS0051
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
Elucigen Biosciences
- 宿主:
Mouse
- 应用范围:
ICC, IHC, IP, Flow
- 浓度:
0.5 mg/mL
- 靶点:
P06756 P05106
- 抗体名:
Anti-Integrin αVβ3, clone LM609-L, Recombinant Mouse Monoclonal Ab
- 规格:
25μg/100μg/500μg
| 规格: | 25μg | 产品价格: | ¥860.0 |
|---|---|---|---|
| 规格: | 100μg | 产品价格: | 询价 |
| 规格: | 500μg | 产品价格: | 询价 |
Integrin αvβ3 is a key receptor involved in cell adhesion, signaling, and migration, mediating interactions between cells and the extracellular matrix (ECM). It is a heterodimer composed of the alpha v (αv) and beta 3 (β3) subunits and plays an essential role in processes such as angiogenesis, wound healing, and tissue remodeling. Integrin αvβ3 is found on various cell types, including endothelial cells, platelets, and immune cells, where it facilitates cellular responses to ECM proteins like fibronectin and vitronectin. It is also implicated in the progression of diseases like cancer, where it contributes to tumor growth, metastasis, and the formation of new blood vessels. Due to its involvement in these critical processes, integrin αvβ3 is a target for therapeutic interventions aimed at inhibiting angiogenesis and tumor progression.
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文献和实验该产品被引用文献
Cheresh, D.A. et al. (2014) Circ Res. 114(1):9-11.
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Anti-Integrin αVβ3, clone LM609-L, Recombinant Mouse Monoclonal Ab
¥860





