Anti-Acetyl-α-Tubulin (Lys40)

Acetyl-α-Tubulin (Lys40) refers to the acetylation of the lysine 40 residue on the α-tubulin protein, a key component of microtubules. This post-translational modification is associated with the regulation of microtubule stability, dynamics, and function. Acetylation at Lys40 is a well-known marker of stable microtubules, and it plays a significant role in cellular processes such as cell division, intracellular transport, and axon growth. This modification can affect the interaction of microtubules with various proteins and motor complexes, contributing to the regulation of cellular architecture and signal transduction. Dysregulation of acetyl-α-tubulin levels has been linked to various diseases, including neurodegenerative disorders and cancer.