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- 英文名：
Rhein Acyl-beta-D-glucuronide
- 库存：
100+
- 供应商：
上海维亦特生物
- CAS号：
190605-03-9
Rhein Acyl-beta-D-glucuronide
190605-03-9
C21H16O12
460.34
No Data Available
No Data Available
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文献和实验Rhein Acyl-beta-D-glucuronide
190605-03-9
C21H16O12
460.34
No Data Available
No Data Available
黑色素瘤治疗最新发现：维生素 D 能抑制 Wnt/beta-catenin 信号通路，降低癌细胞的侵袭能力
11 月 5 日，英国癌症协会（Cancer Research UK）的科学家与英国利兹大学 Newton Bishop 教授和她的团队在知名期刊 Cancer Research 上发表题为 《Vitamin D-VDR signaling inhibits Wnt/beta-catenin-mediated melanoma progression and promotes anti-tumor immunity》 的文章，发现维生素 D 能够抑制黑色素瘤细胞中的 Wnt/beta
In Vitro Assessment of the Reactivity of Acyl Glucuronides
glucuronides are prepared with UDPGA-fortified microsomes and 1-O-β acyl glucuronide is established based on its sensitivity to hydrolysis by β-glucuronidase. The chemical degradation of 1-O-β isomer in 0.1 M phosphate buffer at pH 7.4 is monitored over time
In Vitro Screening Assay of the Reactivity of Acyl Glucuronides
Acyl glucuronides are unstable at physiologic pH and thus can result in free aglycone by hydrolysis and lead to positional isomers by acyl migration. Acylmigrated glucuronide isomers were shown to bind covalently to proteins in vitro
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