2,2,6,6-d4-Morpholine

Delivery of Phosphorodiamidate Morpholino Antisense Oligomers in Cancer Cells

possess a unique structure, in which the deoxyribose moiety of DNA is replaced with a six-membered morpholine ring and the charged phosphodiester internucleoside linkages are replaced with neutral phosphorodiamidate linkages. PMO internalization in uptake

Assessing the Relative Efficacy of Antiretroviral Activity of Different Drugs on Macrophages

, but once infected they can efficiently infect T-cells. The protocols in this chapter can be used to culture HIV in monocytes/macrophages and to study factors such as drugs and chemokines that influence its replication. Support protocols describe the 6-d-adherence

Derivation and Characterization of Gut-Like Structures From Embryonic Stem Cells

development in vivo. The EBs at the 6-d egg-cylinder stage may have the potential to regulate developmental programs associated with cell lineage commitment and provide an appropriate microenvironment to differentiate ES cells into enteric derivatives