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1228105-53-0
MCC-DM1
1228105-53-0
C₄₇H₆₃ClN₄O₁₄S
975.54
White to Pale Yellow Solid
Chloroform (Slightly), Methanol (Slightly)
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文献和实验MCC-DM1
1228105-53-0
C₄₇H₆₃ClN₄O₁₄S
975.54
White to Pale Yellow Solid
Chloroform (Slightly), Methanol (Slightly)
Analysis of CTG Repeats Using DM1 Model Mice
This chapter describes how transgenic mice can be made with human genomic DNA fragments cloned from DM1 patients’ DNA and how the CTG repeat instability is assessed over generations and in different tissues. Construction of cosmid libraries
Cell Recovery from DM1 Transgenic Mouse Tissue to Study (CTG)
Myotonic dystrophy type 1 results from an unstable expanded CTG repeat ((CTG) n ) in the 3′ UTR of the DMPK gene. Transgenic mouse models have been developed to reproduce the (CTG) n instability seen in DM1 patients. These transgenic mice
controversial. In normal individuals, the removal of inhaled pathogens from the airway surface by mucociliary clearance (MCC) forms a major line of lung defense (16 ,17 ). In addition, the antimicrobial properties of airway surface liquid (ASL) contribute
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