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- CAS号：
97682-44-5
(+)-Irinotecan
97682-44-5
C₃₃H₃₈N₄O₆
586.68
White to Brown Solid
Acetonitrile (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
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文献和实验(+)-Irinotecan
97682-44-5
C₃₃H₃₈N₄O₆
586.68
White to Brown Solid
Acetonitrile (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
nodes with high frequency. Firefly luciferase-expressing HT-29 cells were used in this model to realize the benefits of bioluminescence imaging (BLI). A combination of irinotecan, 5-fluorouracil (5-FU), and leucovorin (LV) (IFL) was used as a standard
is involved in the glucuronidation of SN-38, an active metabolite of the anti-cancer drug irinotecan. Single-nucleotide polymorphisms of the UGT1A1 gene have been correlated to irinotecan-induced ADRs. Variant UGT1A1s are heterologously expressed in COS
Purification of DNA Topoisomerase I from Human Placenta
DNA topoisomerase I (topo I) has been firmly established as the molecular target of the camptothecin group of anticancer drugs. These drugs include camptothecin, topotecan, 9-amino-camptothecin, and irinotecan
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