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- CAS号：
856925-71-8
(S)-(-)-Blebbistatin
856925-71-8
C₁₈H₁₆N₂O₂
292.33
Pale Yellow to Yellow Solid
Chloroform (Slightly, Heated), Dichloromethane (Slightly, Soncated), DMSO (Slightly)
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文献和实验(S)-(-)-Blebbistatin
856925-71-8
C₁₈H₁₆N₂O₂
292.33
Pale Yellow to Yellow Solid
Chloroform (Slightly, Heated), Dichloromethane (Slightly, Soncated), DMSO (Slightly)
Enzymatic Synthesis of (S)-Phenylalanine and Related (S)-Amino Acids by Phenylalanine Dehydrogenase
substituents in the reductive amination reaction. Optically pure (S)-phe and other (S)-amino acids are quantitatively synthesized from their oxo-analogs using PheDH, with a regeneration of NADH by formate dehydrogenase from Candida boidinii No. 2201. Acetone
have led to the conclusion that CYP2C19 is a major P450 responsible for (S)-mephenytoin 4’-hydroxylation activity in human liver microsomes (1 , 2 ). This is supported by the finding that cDNA-expressed CYP2C19 has a 50-to lOO-fold greater turnover number
A reverse-phase, high-performance liquid chromatography method is described for the quantification of 4′-hydroxymephenytoin formed enzymatically from 14 C-labeled (S )-mephenytoin following incubation with cDNA-expressed CYP2C19 or human
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