- 询价
- 辰辉创聚生物
- 中国
- NBL-241007
- 2025年07月11日
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- 详细信息
- 技术资料
- 保存条件：
Short term 4℃; Long term -20℃.
- 保质期：
见COA
- 英文名：
Recombinant Mouse IL-17RB, His-tag
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug;1mg;Bulk
| 产品信息
品名:NebuSelect™ Recombinant Mouse IL-17RB, His-tag
货号:NBL-241007
品牌:Nebulabio
规格:100ug；1mg；Bulk
| 产品描述
NebuSelect™ Recombinant Mouse IL-17RB, His-tag(Cat#NBL-241007) is expressed in HEK293 with His tag at the C-Terminus.It contains Arg18-Gly286.
| 产品属性
表达系统:HEK293
标签:His-tag
靶点名称:IL-17RB
物种：Mouse
分子量：The protein has a predicted MW of 30.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
氨基酸序列：Arg18-Gly286
Accession: Q9JIP3-1
纯度:＞95%
内毒素：＜1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.
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