- 询价
- 辰辉创聚生物
- 中国
- NBL-240890
- 2025年07月13日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Short term 4℃; Long term -20℃.
- 保质期：
见COA
- 英文名：
Recombinant Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta, hFc-tag
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug;1mg;Bulk
| 产品信息
品名:NebuSelect™ Recombinant Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta, hFc-tag
货号:NBL-240890
品牌:Nebulabio
规格:100ug；1mg；Bulk
| 产品描述
NebuSelect™ Recombinant Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta, hFc-tag(Cat#NBL-240890) is expressed in HEK293 with hFc tag at the C-Terminus.It contains Gln22-Asp117(CD3E)&Phe22-Ala105(CD3D).
| 产品属性
表达系统:HEK293
标签:hFc-tag
靶点名称:CD3E&CD3D/CD3 epsilon&CD3 delta
物种：Cynomolgus
分子量：The protein has a predicted MW of 36.9 kDa (CD3E) and 35.4 kDa (CD3D). Due to glycosylation,the protein migrates to 58-62 kDa (CD3E) and 44-46 kDa (CD3D) based on Bis-Tris PAGE result.
氨基酸序列：Gln22-Asp117(CD3E) & Phe22-Ala105(CD3D)
Accession: Q95LI5.2(CD3E)&Q95LI8(CD3D)
纯度:＞95%
内毒素：＜1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
T-cell surface glycoprotein CD3 epsilon&CD3 delta chain, also known as CD3E & CD3D , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.
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文献和实验of T-cell activation: CD2, CD3D, CD3E, CD3G, CD4, CD7, CD80, CD86, CD8A, CD8B1, CLECSF12, ICOSL, IRF4, KIF13B, NCK1, NCK2, PRLR, SIT, SLA2, TNFSF14. T-cell proliferation: CD28, CD3E, GLMN, ICOSL, IL10, IL12B, IL18, IL27, NCK1, NCK2, SFTPD, SPP
T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
proliferation. What You Need Materials 1X sterile PBS Anti-mouse CD3e, 145-2C11: Functional Grade, Cat. No. 16-0031 , or Purified, Cat. No. 14-0031 Supplemented RPMI-1640 click
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