- 询价
- 辰辉创聚生物
- 中国
- NBL-240514
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Short term 4℃; Long term -20℃.
- 保质期：
见COA
- 英文名：
Recombinant SARS PLpro/papain-like protease, His-tag
- 库存：
大量
- 供应商：
北京辰辉创聚生物技术有限公司
- 规格：
100ug;1mg;Bulk
| 产品信息
品名:NebuSelect™ Recombinant SARS PLpro/papain-like protease, His-tag
货号:NBL-240514
品牌:Nebulabio
规格:100ug；1mg；Bulk
| 产品描述
NebuSelect™ Recombinant SARS PLpro/papain-like protease, His-tag(Cat#NBL-240514) is expressed in E.coli with His tag at the C-terminus.It contains Glu1541-Tyr1859.
| 产品属性
表达系统:E.coli
标签:His-tag
靶点名称:PLpro/papain-like protease
物种：SARS
分子量：The protein has a predicted MW of 36.91 kDa same as Bis-Tris PAGE result.
氨基酸序列：Glu1541-Tyr1859
Accession: AAX16193.1
纯度:＞95%
内毒素：＜1EU/ug(LAL Method)
储存运输条件: Short term 4℃; Long term -20℃.
| 靶点信息
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.
For Research Use Only!
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文献和实验to as clostridiopeptidase A which is a protease with a specificity for the X-Gly bond in the sequence Pro-X-Gly-Pro, where X is most frequently a neutral amino acid. Such sequences are often found in collagen, but only rarely in other proteins. While many proteases
/α、Loop/β或α/β间的二级结构转换构成蛋白质活性调节的开关. 3 前体肽辅助蛋白质折叠 一些蛋白酶, 如subtilisin, α-lytic protease和papain等, 新合成的蛋白质产物含有一段前体肽. 前体蛋白能够自发地折叠成正确的三维空间结构. 然后通过蛋白酶的自身酶解切除前体肽, 得到有蛋白酶水解活性的成熟蛋白酶. 虽然成熟蛋白是相当稳定的, 但若通过体外变性, 却不能重新折叠成有生物活性的功能蛋白. 可是, 如果在复性过程中加入前体
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