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- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
Hypoxanthine
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
68-94-0
分子式：C5H4N4O
分子量：136.11
溶剂：DMSO (>25 mg/ml)
性状：Off-white solid
存储：-20°C
Activity (short version)：Nutrient additive for cell culture
Function / Pharmacology：Hypoxanthine is a natural purine analog and a breakdown product of adenosine.1 Together with aminopterin and thymidine, it is a component of HAT medium2, which is used to select clones during recombinant protein and antibody production, particularly important in bioprocessing. It is a biomarker of ischemia2,3, and it is used in malaria research as an essential nutrient for P. Falciparum4. It also can enable stem cell expansion.5
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文献和实验6-羟基嘌呤。与黄嘌呤一起，广泛存在于动植物体中，其核苷酸的肌苷酸是核酸的嘌呤核苷酸的前体。也是咖啡因的母体。次黄嘌呤可以通过腺嘌呤脱氨酶或亚硝酸的作用由腺嘌呤脱氨生成，也能通过核苷磷酸化酶使肌苷发生磷酸解而失成。通过黄嘌呤氧比酶可被氧化成尿酸，认为这是嘌呤碱的主要分解途经。
Description In vitro whole cell assay by [H3] Hypoxanthine uptake assay Procedure [H3] Hypoxanthine uptake assay (with respect to red blood cell cultures of P. falciparum Dispense 25 ul complete RPMI in different wells (triplicate
Description In vitro whole cell assay by [H3] Hypoxanthine uptake assay Procedure [H3] Hypoxanthine uptake assay (with respect to red blood cell cultures of P. falciparum Dispense 25 ul complete RPMI in different wells (triplicate
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