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- 文献和实验
- 技术资料
- 保存条件：
-20°C
- 保质期：
咨询
- 英文名：
IM156
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
1422365-93-2
纯度：>98% by HPLC；NMR (Conforms)
分子式：C13H16F3N5O
分子量：315.3
溶剂：DMSO (25 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：AMPK activator/Mitochondrial protein complex I inhibitor
Function / Pharmacology：Potent activator of AMP-activated protein kinase (AMPK) showing greater activity than metformin or AICAR.1 It displayed protective effects in vivo against peritoneal1, liver2, renal3,and pulmonary fibrosis4. IM156 induces metabolic stress in Myc+ lymphoma cells by inhibiting TCA cycle metabolism and mitochondrial respiration (inhibits mitochondrial protein complex 1).4 IM156 acts as an antiproliferative in several cancer models.5-7
分子式：C13H16F3N5O
分子量：315.3
溶剂：DMSO (25 mg/ml)
性状：White solid
存储：-20°C
Activity (short version)：AMPK activator/Mitochondrial protein complex I inhibitor
Function / Pharmacology：Potent activator of AMP-activated protein kinase (AMPK) showing greater activity than metformin or AICAR.1 It displayed protective effects in vivo against peritoneal1, liver2, renal3,and pulmonary fibrosis4. IM156 induces metabolic stress in Myc+ lymphoma cells by inhibiting TCA cycle metabolism and mitochondrial respiration (inhibits mitochondrial protein complex 1).4 IM156 acts as an antiproliferative in several cancer models.5-7
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文献和实验该产品被引用文献
1422365-93-2
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IM156
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