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- 保存条件:
-20°C
- 保质期:
咨询
- 英文名:
Piperine
- 库存:
1000+
- 供应商:
上海维亦特生物
- CAS号:
94-62-2
纯度:98% by HPLC,;NMR (Conforms)
分子式:C17H19NO3
分子量:285.34
溶剂:DMSO (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Up-regulates skeletal muscle metabolism
Function / Pharmacology:Piperine is a natural product isolated from black pepper that has myriad biological effects. Piperine has recently been shown to increase the metabolic rate of resting muscle (fast twitch skeletal fibers) without effecting slow twitch or cardiac fibers via destabilization of the super-relaxed state of myosin heads.1 This is proposed as a mechanism for the mitigation of obesity and type 2 diabetes by piperine. Piperine is an agonist at the TRPV1 receptor (EC50 = 38 µM).2 Piperine has various effects on drug metabolism3, inhibits human P-glycoprotein and CYP3A44 as well as UDP-glucose dehydrogenase and glucuronidation5
分子式:C17H19NO3
分子量:285.34
溶剂:DMSO (>25 mg/ml)
性状:Off-white solid
存储:-20°C
Activity (short version):Up-regulates skeletal muscle metabolism
Function / Pharmacology:Piperine is a natural product isolated from black pepper that has myriad biological effects. Piperine has recently been shown to increase the metabolic rate of resting muscle (fast twitch skeletal fibers) without effecting slow twitch or cardiac fibers via destabilization of the super-relaxed state of myosin heads.1 This is proposed as a mechanism for the mitigation of obesity and type 2 diabetes by piperine. Piperine is an agonist at the TRPV1 receptor (EC50 = 38 µM).2 Piperine has various effects on drug metabolism3, inhibits human P-glycoprotein and CYP3A44 as well as UDP-glucose dehydrogenase and glucuronidation5
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文献和实验该产品被引用文献
94-62-2
相关实验
采收,用水浸渍数日,去外果皮晒干,则果实表面呈白色,称白胡椒。果实成分有胡椒碱( piperine)、胡椒脂碱( chavicine)、胡椒新碱( piperanine),挥发油含向日葵素( piperonal)、二氢葛缕醇( dihydrocarveol)、氧化石竹烯( caryophyllene oxi- de)、隐品酮( cryptone)等。胡椒味辛辣,但刺激性比辣椒小,除供调味外,药用内服作驱风健胃剂,外用可作刺激剂、发热剂。胡椒原产东南亚,中国广东、广西、云南、台湾引种。此外中国南部尚
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Piperine
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