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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
RT
- 保质期：
咨询
- 英文名：
Bedaquiline
- 库存：
1000+
- 供应商：
上海维亦特生物
- CAS号：
843663-66-1
纯度：99% by HPLC,；NMR (Conforms)
分子式：C32H31BrN2O2
分子量：555.50
溶剂：DMSO (10 mg/ml)
性状：White solid
存储：RT
Activity (short version)：Antituberculosis / SARS-CoV2 3CLpro inhibitor
Function / Pharmacology：Bedaquiline is a clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains.1 It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE)2 and subunit 3 of ATP synthase inhibiting ATP production.4 Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro.5
分子式：C32H31BrN2O2
分子量：555.50
溶剂：DMSO (10 mg/ml)
性状：White solid
存储：RT
Activity (short version)：Antituberculosis / SARS-CoV2 3CLpro inhibitor
Function / Pharmacology：Bedaquiline is a clinically useful antituberculosis agent that is active (MIC’s 0.030 to 0.120 µg/mL) against multi-drug resistant strains.1 It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE)2 and subunit 3 of ATP synthase inhibiting ATP production.4 Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro.5
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文献和实验该产品被引用文献
843663-66-1
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Bedaquiline
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